Title: Computational Methods for Drug Carrier Design in the Microvasculature

Speaker: Tae-Rin Lee, Ph.D. (Senior Researcher, AICT)

Date & Time: 2016. 11. 30. 수요일 17:00

Where: 융대원 D-122호

 

Abstract

For the design of drug carriers (or nano-vehicles), it is crucial to understand how they are circulated in the human body. However, it is still challenging to predict the journey of drug carriers only by in vivo experiments. In this reason, mathematical and computational models are helpful to capture their dynamics in the microvasculature.
In this talk, I will introduce how to predict the dynamics of drug carriers in the multiscale nature of human body. First, the immersed type computational methods will be utilized for whole blood simulation with drug carriers in small vessels. Second, mathematically generated microvasculature will be compared with in vivo experiments. Third, angiogenesis in tumor environment is modeled by considering vessel growth factors, oxygen level, and tumor growth rate. In the end of this talk, the future direction of in silico models will be briefly discussed.

 

Biography

학력

성균관대학교 기계공학부 학사[1999-2004]
성균관대학교 기계공학과 석사[2004-2006]
성균관대학교 나노과학기술협동학부 박사[2006-2010]

 
경력

Postdoctoral Researcher, Mechanical Engineering, Northwestern University [2011-2012]
Postdoc, Dept. of Nanomedicine, Methodist Hospital 연구소, Texas Medical Center [2012-2013]
책임연구원, 삼성 제일모직[2013-2014]
선임연구원, 서울대학교 차세대융합기술연구원[2014-현재]

 

초청자 : 융합과학부 나노융합전공 송윤규 교수 (연락처 : 031-888-9133, songyk@snu.ac.kr)